Disentangling the genetics of lean mass. Karasik, D., Zillikens, M., Hsu, Y., Aghdassi, A., Akesson, K., Amin, N., Barroso, I., Bennett, D., Bertram, L., Bochud, M., Borecki, I., Broer, L., Buchman, A., Byberg, L., Campbell, H., Campos-Obando, N., Cauley, J., Cawthon, P., Chambers, J., Chen, Z., Cho, N., Choi, H., Chou, W., Cummings, S., De Groot, L., De Jager, P., Demuth, I., Diatchenko, L., Econs, M., Eiriksdottir, G., Enneman, A., Eriksson, J., Eriksson, J., Estrada, K., Evans, D., Feitosa, M., Fu, M., Gieger, C., Grallert, H., Gudnason, V., Lenore, L., Hayward, C., Hofman, A., Homuth, G., Huffman, K., Husted, L., Illig, T., Ingelsson, E., Ittermann, T., Jansson, J., Johnson, T., Biffar, R., Jordan, J., Jula, A., Karlsson, M., Khaw, K., Kilpeläinen, T., Klopp, N., Kloth, J., Koller, D., Kooner, J., Kraus, W., Kritchevsky, S., Kutalik, Z., Kuulasmaa, T., Kuusisto, J., Laakso, M., Lahti, J., Lang, T., Langdahl, B., Lerch, M., Lewis, J., Lill, C., Lind, L., Lindgren, C., Liu, Y., Livshits, G., Ljunggren, ., Loos, R., Lorentzon, M., Luan, J., Luben, R., Malkin, I., McGuigan, F., Medina-Gomez, C., Meitinger, T., Melhus, H., Mellström, D., Michaëlsson, K., Mitchell, B., Morris, A., Mosekilde, L., Nethander, M., Newman, A., O’Connell, J., Oostra, B., Orwoll, E., Palotie, A., Peacock, M., Perola, M., Peters, A., Prince, R., Psaty, B., Räikkönen, K., Ralston, S., Ripatti, S., Rivadeneira, F., Robbins, J., Rotter, J., Rudan, I., Salomaa, V., Satterfield, S., Schipf, S., Shin, C., Smith, A., Smith, S., Soranzo, N., Spector, T., StanÄ Áková, A., Stefansson, K., Steinhagen-Thiessen, E., Stolk, L., Streeten, E., Styrkarsdottir, U., Swart, K., Thompson, P., Thomson, C., Thorleifsson, G., Thorsteinsdottir, U., Tikkanen, E., Tranah, G., Uitterlinden, A., Van Duijn, C., Van Schoor, N., Vandenput, L., Vollenweider, P., Völzke, H., Wactawski-Wende, J., Walker, M., Wareham, N., Waterworth, D., Weedon, M., Wichmann, H., Widen, E., Williams, F., Wilson, J., Wright, N., Yerges-Armstrong, L., Yu, L., Zhang, W., Zhao, J., Zhou, Y., Nielson, C., Harris, T., Demissie, S., Kiel, D., Ohlsson, C. Am J Clin Nutr. 2019 Feb 1;109(2):276-287. doi: 10.1093/ajcn/nqy272.
Genome-wide association study for radiographic vertebral fractures: a potential role for the 16q24 BMD locus. Oei L, Estrada K, Duncan EL, Christiansen C, Liu CT, Langdahl BL, Obermayer-Pietsch B, Riancho JA, Prince RL, van Schoor NM, McCloskey E, Hsu YH, Evangelou E, Ntzani E, Evans DM, Alonso N, Husted LB, Valero C, Hernandez JL, Lewis JR, Kaptoge SK, Zhu K, Cupples LA, Medina-Gómez C, Vandenput L, Kim GS, Hun Lee S, Castaño-Betancourt MC, Oei EH, Martinez J, Daroszewska A, van der Klift M, Mellström D, Herrera L, Karlsson MK, Hofman A, Ljunggren Ö, Pols HA, Stolk L, van Meurs JB, Ioannidis JP, Zillikens MC, Lips P, Karasik D, Uitterlinden AG, Styrkarsdottir U, Brown MA, Koh JM, Richards JB, Reeve J, Ohlsson C, Ralston SH, Kiel DP, Rivadeneira F. Bone. 2014 Feb;59:20-7.
Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium.Moayyeri A, Hsu YH, Karasik D, Estrada K, Xiao SM, Nielson C, Srikanth P, Giroux S, Wilson SG, Zheng HF, Smith AV, Pye SR, Leo PJ, Teumer A, Hwang JY, Ohlsson C, McGuigan F, Minster RL, Hayward C, Olmos JM, Lyytikäinen LP, Lewis JR, Swart KM, Masi L, Oldmeadow C, Holliday EG, Cheng S, van Schoor NM, Harvey NC, Kruk M, del Greco M F, Igl W, Trummer O, Grigoriou E, Luben R, Liu CT, Zhou Y, Oei L, Medina-Gomez C, Zmuda J, Tranah G, Brown SJ, Williams FM, Soranzo N, Jakobsdottir J, Siggeirsdottir K, Holliday KL, Hannemann A, Go MJ, Garcia M, Polasek O, Laaksonen M, Zhu K, Enneman AW, McEvoy M, Peel R, Sham PC, Jaworski M, Johansson Å, Hicks AA, Pludowski P, Scott R, Dhonukshe-Rutten RA, van der Velde N, Kähönen M, Viikari JS, Sievänen H, Raitakari OT, González-Macías J, Hernández JL, Mellström D, Ljunggren O, Cho YS, Völker U, Nauck M, Homuth G, Völzke H, Haring R, Brown MA, McCloskey E, Nicholson GC, Eastell R, Eisman JA, Jones G, Reid IR, Dennison EM, Wark J, Boonen S, Vanderschueren D, Wu FC, Aspelund T, Richards JB, Bauer D, Hofman A, Khaw KT, Dedoussis G, Obermayer-Pietsch B, Gyllensten U, Pramstaller PP, Lorenc RS, Cooper C, Kung AW, Lips P, Alen M, Attia J, Brandi ML, de Groot LC, Lehtimäki T, Riancho JA, Campbell H, Liu Y, Harris TB, Akesson K, Karlsson M, Lee JY, Wallaschofski H, Duncan EL, O’Neill TW, Gudnason V, Spector TD, Rousseau F, Orwoll E, Cummings SR, Wareham NJ, Rivadeneira F, Uitterlinden AG, Prince RL, Kiel DP, Reeve J, Kaptoge SK. Hum Mol Genet. 2014 Jun 1;23(11):3054-68.
A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus. Oei L, Hsu YH, Styrkarsdottir U, Eussen BH, de Klein A, Peters MJ, Halldorsson B, Liu CT, Alonso N, Kaptoge SK, Thorleifsson G, Hallmans G, Hocking LJ, Husted LB, Jameson KA, Kruk M, Lewis JR, Patel MS, Scollen S, Svensson O, Trompet S, van Schoor NM, Zhu K, Buckley BM, Cooper C, Ford I, Goltzman D, González-Macías J, Langdahl BL, Leslie WD, Lips P, Lorenc RS, Olmos JM, Pettersson-Kymmer U, Reid DM, Riancho JA, Slagboom PE, Garcia-Ibarbia C, Ingvarsson T, Johannsdottir H, Luben R, Medina-Gómez C, Arp P, Nandakumar K, Palsson ST, Sigurdsson G, van Meurs JB, Zhou Y, Hofman A, Jukema JW, Pols HA, Prince RL, Cupples LA, Marshall CR, Pinto D, Sato D, Scherer SW, Reeve J, Thorsteinsdottir U, Karasik D, Richards JB, Stefansson K, Uitterlinden AG, Ralston SH, Ioannidis JP, Kiel DP, Rivadeneira F, Estrada K. J Med Genet. 2014 Feb;51(2):122-31.
Multistage genome-wide association meta-analyses identified two new loci for bone mineral density. Zhang L, Choi HJ, Estrada K, Leo PJ, Li J, Pei YF, Zhang Y, Lin Y, Shen H, Liu YZ, Liu Y, Zhao Y, Zhang JG, Tian Q, Wang YP, Han Y, Ran S, Hai R, Zhu XZ, Wu S, Yan H, Liu X, Yang TL, Guo Y, Zhang F, Guo YF, Chen Y, Chen X, Tan L, Zhang L, Deng FY, Deng H, Rivadeneira F, Duncan EL, Lee JY, Han BG, Cho NH, Nicholson GC, McCloskey E, Eastell R, Prince RL, Eisman JA, Jones G, Reid IR, Sambrook PN, Dennison EM, Danoy P, Yerges-Armstrong LM, Streeten EA, Hu T, Xiang S, Papasian CJ, Brown MA, Shin CS, Uitterlinden AG, Deng HW. Hum Mol Genet. 2014 Apr 1;23(7):
A predictive model for knee joint replacement in older women. Lewis JR, Dhaliwal SS, Zhu K, Prince RL. PLoS ONE 2013;8:
Associations of proanthocyanidin intake with renal function and clinical outcomes in elderly women. Ivey KL, Lewis JR, Lim WH, Lim EM, Hodgson JM, Prince RL PLoS ONE 2013;8:e71166.
Association of dairy intake with body composition and physical function in older community-dwelling women. Radavelli-Bagatini S, Zhu K, Lewis JR, Dhaliwal SS, Prince RL. Journal of the Academy of Nutrition and Dietetics 2013;113:1669-74.
Tea and non-tea flavonol intakes in relation to atherosclerotic vascular disease mortality in older women. Ivey KL, Lewis JR, Prince RL, Hodgson JM. The British journal of nutrition 2013;110:1648-55.]
Effects of the Assessment of 4 Determinants of Structural Geometry on QCT- and DXA-Derived Hip Structural Analysis Measurements in Elderly Women. Khoo BC, Brown K, Zhu K, Price RI, Prince RL. Journal of Clinical Densitometry : 2014;17:38
Five-year decline in estimated glomerular filtration rate associated with a higher risk of renal disease and atherosclerotic vascular disease clinical events in elderly women. Lim WH, Lewis JR, Wong G, et al. QJM : 2013;106:443-50.
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Estrada K, Styrkarsdottir U, Evangelou E, Hsu YH, Duncan EL et al. Nat Genet. 2012 Apr 15;44(5):491-501.
Adverse events from calcium supplementation: relationship to errors in myocardial infarction self-reporting in randomized controlled trials of calcium supplementation. Lewis JR, Zhu K, Prince RL. J Bone Miner Res. 2012 Mar;27(3):719-22.
An in vivo comparison of hip structure analysis (HSA) with measurements obtained by QCT. Ramamurthi K, Ahmad O, Engelke K, Taylor RH, Zhu K, Gustafsson S, et al. Osteoporos Int. 2012 23:543–551
Differences in structural geometrical outcomes at the neck of the proximal femur using two-dimensional DXA-derived projection (APEX) and three-dimensional QCT-derived (BIT QCT) techniques. Khoo BC, Brown K, Zhu K, Pollock M, Wilson KE, Price RL, et al. Osteoporos Int. 2012 23:1393–1398.
The calcium scare: response to Bolland et al. Nordin BE, Lewis JR, Daly RM, Prince RL. Osteoporos Int. 2011 Dec;22(12):3081–3.
Association between yogurt, milk, and cheese consumption and common carotid artery intima-media thickness and cardiovascular disease risk factors in elderly women.Ivey KL, Lewis JR, Hodgson JM, Zhu K, Dhaliwal SS, Thompson PL, et al. Am J Clin Nutr. 2011 Jul;94(1):234-9.
Calcium supplementation and the risks of atherosclerotic vascular disease in older women: results of a 5-year RCT and a 4.5-year follow-up.Lewis JR, Calver J, Zhu K, Flicker L, Prince RL J Bone Miner Res. 2011 Jan;26(1):35-41.
Significant association between common polymorphisms in the aromatase gene CYP19A1 and bone mineral density in postmenopausal women. Mullin BH, Carter KW, Lewis JR, Ingley E, Wilson SG, Prince RL.Calcif Tissue Int. 2011 Dec;89(6):464-71.
‘Timed up and go’ test and bone mineral density measurement for fracture prediction. Zhu K, Devine A, Lewis JR, Dhaliwal SS, Prince RL. Arch Intern Med. 2011 Oct 10;171(18):1655-61.
A non-synonymous coding change in the CYP19A1 gene Arg264Cys (rs700519) does not affect circulating estradiol, bone structure or fracture. Wang JZ, Deogan MS, Lewis JR, Chew S, Mullin BH, McNab TJ, et al. BMC Med Genet. 2011 Dec 20;12(1):165.
Homozygous deletion of the UGT2B17 gene is not associated with osteoporosis risk in elderly Caucasian women. Chew S, Mullin BH, Lewis JR, Spector TD, Prince RL, Wilson SG. Osteoporos Int. 2011 Jun;22(6):1981-6.
Reply to “Calcium supplements and cardiovascular risk”. Lewis JR, Calver J, Zhu K, Flicker L, Prince RL. J Bone Miner Res:epub2011/01/06
Evidence of harm is unconvincing.Prince RL, Zhu K, Lewis JR. BMJ. 2011;342:d3541.
Adequacy and change in nutrient and food intakes with aging in a seven-year cohort study in elderly women. Zhu K, Devine A, Suleska A, Tan CY, Toh CZ, Kerr D, Prince RL. J Nutr Health Aging 2010 14(9):723-9.
Habitual chocolate intake and vascular disease: a prospective study of clinical outcomes in older women.Lewis JR, Prince RL, Zhu K, Devine A, Thompson PL, Hodgson JM. Arch Intern Med. 2010 170(20):1857-8.
Volumetric DXA (VXA) – a new method to extract 3D information from multiple in vivo DXA images. Ahmad O, Ramamurthi K, Wilson KE, Engelke K, Prince RL, Taylor RH. J Bone Miner Res. 2010 25:2468-75.
The effects of high potassium consumption on bone mineral density in a prospective cohort study of elderly postmenopausal women.Zhu K, Devine A, Prince RL. Osteoporos Int. 2009 20(2):335-40.
The effects of homocysteine and MTHFR genotype on hip bone loss and fracture risk in elderly women. Zhu K, Beilby J, Dick IM, Devine A, Soos M, Prince RL. Osteoporos Int. 2009 20(7):1183-91.
A cohort study of the effects of serum OPG and OPG gene polymorphisms on cardiovascular mortality in elderly women.Ueland T, Wilson SG, Amirul Islam FM, Mullin B, Devine A, Bollerslev J, Zhu K, Prince RL. Clin Endocrinol (Oxf). 2009 17(6):828-833.
Common variants in the region around Osterix are associated with bone mineral density and growth in childhood. Timpson NJ, Tobias JH, Richards JB, Soranzo N, Duncan EL, Sims AM, Whittaker P, Kumanduri V, Zhai G, Glaser B, Eisman J, Jones G, Nicholson G, Prince R, Seeman E, Spector T, Brown MA, Peltonen L, Smith GD, Deloukas P, Evans DM. Hum Mol Genet. 2009 18(8):1510-7.
A 5-Year Cohort Study of the Effects of High Protein Intake on Lean Mass and Bone Mineral Content in Elderly Postmenopausal Women.Meng X, Zhu K, Devine A, Kerr DA, Binns CW, Prince RL. J Bone Miner Res. 2009
Comparison of QCT-derived and DXA-derived areal bone mineral density and T scores.Khoo BC, Brown K, Cann C, Zhu K, Henzell S, Low V, Gustafsson S, Price RI, Prince RL. Osteoporos Int. 2009 20(9):1539-45.
Effects of calcium and vitamin D supplementation on hip bone mineral density and calcium-related analytes in elderly ambulatory Australian women: a five-year randomized controlled trial. Zhu K, Devine A, Dick IM, Wilson SG, Prince RL. J Clin Endocrinol Metab 2008;93(3):743-9.
Chocolate consumption and bone density in older women.Hodgson JM, Devine A, Burke V, Dick IM, Prince RL. Am J Clin Nutr 2008;87(1):175-80.
Identification of a role for the ARHGEF3 gene in postmenopausal osteoporosis. .Mullin BH, Prince RL, Dick IM, Hart DJ, Spector TD, Dudbridge F, et al. Am J Hum Genet 2008;82(6):1262-9.
Bone structural effects of variation in the TNFRSF1B gene encoding the tumor necrosis factor receptor 2. Mullin BH, Prince RL, Dick IM, Islam FM, Hart DJ, Spector TD, et al. Osteoporos Int 2008;19(7):961-8.
Association of back pain frequency with mortality, coronary heart events, mobility, and quality of life in elderly women.Zhu K, Devine A, Dick IM, Prince RL. Spine 2007;32:2012-8.
The clinical utility of measured kyphosis as a predictor of the presence of vertebral deformities. Prince RL, Devine A, Dick IM. Osteoporos Int 2007;18:621-7.
A cohort study of the effect of endogenous estrogen on spine fracture risk and bone structure in elderly women and an assessment of its diagnostic usefulness.Prince RL, Dick IM, Beilby J, Dhaliwal SS, Devine A. Bone 2007;41:33-8.
Geometric indices of bone strength are associated with physical activity and dietary calcium intake in healthy older women.Nurzenski MK, Briffa NK, Price RI, Khoo BC, Devine A, Beck TJ, Prince RL. J Bone Miner Res 2007;22:416-24.
No associations between OPG gene polymorphisms or serum levels and measures of osteoporosis in elderly Australian women. Ueland T, Bollerslev J, Wilson SG, Dick IM, Islam FM, Mullin BH, Devine A, Prince RL. Bone 2007;40:175-81.
Tea drinking is associated with benefits on bone density in older women. Am J Clin Nutr 2007;86:1243-7.Devine A, Hodgson JM, Dick IM, Prince RL.
Effects of calcium supplementation on clinical fracture and bone structure: results of a 5-year, double-blind, placebo-controlled trial in elderly women.Prince RL, Devine A, Dhaliwal SS, Dick IM. Arch Intern Med 2006;166:869-75.
Do sleep problems or urinary incontinence predict falls in elderly women? Teo JSH, Briffa K, Devine A, et al. Australian Journal of Physiotherapy 2006;52:19-24.
Drinking tea is associated with lower plasma total homocysteine in older women.Hodgson JM, Devine A, Puddey IB, Beilby J, Prince RL. Asia Pac J Clin Nutr 2006;15:253-8.
Prediction of incident osteoporotic fractures in elderly women using the free estradiol index.Devine A, Dick IM, Dhaliwal SS, Naheed R, Beilby J, Prince RL. Osteoporos Int 2005;16:216-221.
Effects of endogenous estrogen on renal calcium and phosphate handling in elderly women. Dick IM, Devine A, Beilby J, Prince RL. Am J Physiol Endocrinol Metab 2005;288:E430-5.
LRP5 gene polymorphisms predict bone mass and incident fractures in elderly Australian women.Bollerslev J, Wilson SG, Dick IM, Islam FM, Ueland T, Palmer L, Devine A, Prince RL. Bone 2005;36:599-606.
Bone mass effects of a BMP4 gene polymorphism in postmenopausal women.Ramesh Babu L, Wilson SG, Dick IM, Islam FM, Devine A, Prince RL. Bone 2005;36:555-61.
Association of an aromatase TTTA repeat polymorphism with circulating estrogen, bone structure, and biochemistry in older women.Dick IM, Devine A, Prince RL. Am J Physiol Endocrinol Metab 2005;288:E989-95.
Klotho gene polymorphisms are associated with osteocalcin levels but not bone density of aged postmenopausal women. Mullin, BH, Wilson, SG, Islam, FMA, Dick, IM, Devine, A, Prince, RL. Calcif Tissue Int 2005;77:145-51.
In vivo short-term precision of hip structure analysis variables in comparison with bone mineral density using paired dual-energy X-ray absorptiometry scans from multi-center clinical trials. Khoo, BC, Beck, TJ, Qiao, QH, Parakh, P, Semanick, L, Prince, RL, Singer, KP, Price, RI.Bone 2005; 37: 112-121.
Protein consumption is an important predictor of lower limb bone mass in elderly women. Devine, A, Dick, IM, Islam, AFM, Dhaliwal, SS, Prince, RL. American Journal of Clinical Nutrition 2005; 81: 1423-1428.
Calcium-Sensing Receptor Gene Polymorphism A986S Does Not Predict Serum Calcium Level, Bone Mineral Density, Calcaneal Ultrasound Indices, or Fracture Rate in a Large Cohort of Elderly Women.Bollerslev J, Wilson SG, Dick IM, Devine A, Dhaliwal SS, Prince RL. Calcif Tissue Int 2004;74(1):12-17.
Phenolic acid metabolites as biomarkers for tea- and coffee- derived polyphenol exposure in human subjects. Hodgson JM, Chan SY, Puddey IB, Devine A, Wattanapenpaiboon N, Wahlqvist ML, et al. British Journal of Nutrition 2004;91(2):301-306.
Physical Activity and Calcium Consumption Are Important Determinants of Lower Limb Bone Mass in Older Women‘,Devine, A., Dhaliwal, S.S., Dick, I.M., Bollerslev, J., Prince, R.L. Journal of Bone and Mineral Research 2004; 19: 1634-39.
Expression of the HFE haemochromatosis gene in a community-based population of elderly females. Rossi JA, Kuek C, Beilby JP, Jeffrey GP, Devine A, L. PR. Journal of Gastroenterology and Hepatology 2004; 19:1150-54.
Prevalence of lower extremity pain and its association with functionality and quality of life in elderly women in Australia. Chen J, Devine A, Dick IM, Dhaliwal SS, Prince RL. Journal of Rheumatology. 2003;30(12):2689-93.
Comparison of genome screens for two independent cohorts provides replication of suggestive linkage of bone mineral density to 3p21 and 1p36. Wilson SG, Reed PW, Bansal A, Chiano M, Lindersson M, Langdown M, et al. Am J Hum Genet 2003;72(1):144-55.
Impact of the analysis of a bone density reference range on determination of the T-score. Price RI, Walters MJ, Retallack RW, Henderson NK, Kerr D, Henzell S, et al. J Clin Densitom 2003;6:51-62.
Tea intake is inversely related to blood pressure in older women. Hodgson JM, Devine A, Puddey IB, Chan SY, Beilin LJ, Prince RL. J Nutr 2003;133(9):2883-86.
Comparison of Pencil-Beam and Fan-Beam DXA Systems. Henzell S, Dhaliwal SS, Price RI, Gill F, Ventouras C, Green C, et al. J Clin Densitom 2003;6:205-10.
The T869C TGF beta polymorphism is associated with fracture, bone mineral density, and calcaneal quantitative ultrasound in elderly women. Dick IM, Devine A, Li S, Dhaliwal SS, Prince RL. Bone 2003;33(3):335-41.
Apolipoprotein E4 is associated with reduced calcaneal quantitative ultrasound measurements and bone mineral density in elderly women. Dick IM, Devine A, Marangou A, Dhaliwal SS, Laws S, Martins RN, et al. Bone 2002;31(4):497-502.
Effects of vitamin D metabolites on intestinal calcium absorption and bone turnover in elderly women. Devine A, Wilson SG, Dick IM, Prince RL.Am J Clin Nutr 2002;75(2):283-8.
Recreational physical activity levels in healthy older women: the importance of fear of falling. Bruce DG, Devine A, Prince RL. J Am Geriatr Soc 2002;50(1):84-9.
Lifetime and five-year age-specific risks of first and subsequent osteoporotic fractures in postmenopausal women. Doherty DA, Sanders KM, Kotowicz MA, Prince RL. Osteoporos Int 2001;12(1):16-23.
Effects of zinc and other nutritional factors on insulin-like growth factor I and insulin-like growth factor binding proteins in postmenopausal women. Devine A, Rosen C, Mohan S, Baylink D, Prince RL. Am J Clin Nutr 1998;68(1):200-6.